Cancer
is a process of rapid abnormal division, multiplication and proliferation of
cells that could spread from one organ to another by a process known as
metastasis.
 |
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A benign type of cancer
is the one in which cancer or tumor is limited to an organ and does not affect
other organs.
Malignant types of
cancers are those which undergo the process of metastasis and damage more than
one parts of body. Such types of cancers are always difficult to treat as they
produce more catastrophic effects.
The treatment of cancer
is quite complicated and various anti-cancer drugs are commonly prescribed by
oncologists.
Here you find a list of
anti-cancer drugs having herbal origin.
No.
|
Class
|
Name
of drug
|
Botanical
origin
|
Type
of Cancer
|
1.
|
Vinca alkaloids
|
Vincristine
Vinblastine
|
Catharanthus roseus
(Apocynaceae)
|
Hodgkin’s disease
Lymphomas
Carcinoma Breast
Testicular tumors
|
2.
|
Taxanes
|
Paclitaxel
Docetaxel
|
Taxus brevifolia
(Taxaceae)
|
Ovarian cancer
Lung carcinoma
Gastric & Cervical
cancers
Prostate & colon
cancer
|
3.
|
Epipodophyllotoxin
|
Etoposide
|
Podophyllum hexandrum
(Berberidaceae)
|
Lung cancer (small cell lung cancer; SCLC)
|
04
|
Topotecan
Irinotecan
|
Camptotheca acuminata (Nyssaceae)
|
Camptothecin analouges
|
Ovarian
cancers
Colorectal
cancer
Cancer
of neck & head
Liver
cancer
|
Colchicine
|
Demecolcine
|
Cocus cholchicum
Autumnale (Liliaceae)
|
Chemotherapy
|
|
6.
|
Maytansinoid
|
Mcytanacine
Maytansine
|
Maytenus buchananii,
M.Serrata (Celastraceae)
|
Chemotherapy
|
7.
|
Macrocyclic lactones
|
Bryostatins
|
Bryozoa Bugula neritina
|
Under
investigation
|
8.
|
Quassinoids
|
Bruceantin brusato
|
Brucea javanica
(Simarubaceae)
|
Leukemia
Colon
cancer
|
9.
|
Curcuma
|
Curcumin
|
Curcuma longa
(Zingiberaceae)
|
Colon
cancer
Bladder
cancer
Breast
cancer
|
10.
|
Flavonoids
|
Vicenin
Orentin
|
Ocimum sanctum
(Labiatae)
|
Prostate
cancer
|
11.
|
Sesquiterpene
|
Gossypal
|
Gossypium barbadense
(Gossypiaceae)
|
Chemotherapy
|
12.
|
Ellipticine
|
Ellipticine
|
Ochrosia eliptica
(Apocynaceae)
|
Leukemia
|
13.
|
Pthalide isoquinoline
alkaloid
|
Noscapine
|
Papaver somniferum
(Papaveraceae)
|
Prostate
cancer
|
14.
|
Acetogenins
|
Acetogenin
|
Annona species
(Annonaceae)
|
Chemotherapy
|
References:
- Reason Wilken et al. Curcumin: A
review of anti-cancer properties and therapeutic activity in head and neck
squamous cell carcinoma. Mol Cancer. 2011; 10: 12.
- Jordan, Mary Ann; Wilson, Leslie
(2004). "Microtubules as a target for anticancer
drugs". Nature reviews. Cancer 4 (4): 253–65.
- Lokesh Dalasanur. Anti-cancer
effects of novel flavonoid vicenin-2 as a single agent and in synergistic
combination with docetaxel in prostate cancer. Biochem Pharmacol 2011
Nov 23;82(9):1100-9. Epub 2011 Jul 23.
- Kamei J (1996). "Role of
opioidergic and serotonergic mechanisms in cough and
antitussives". Pulmonary pharmacology 9 (5–6): 349–356
- Zhou J, Gupta K, Aggarwal S, Aneja
R, Chandra R, Panda D, Joshi HC (2003). "Brominated derivatives of
noscapine are potent microtubule-interfering agents that perturb mitosis
and inhibit cell proliferation". Mol
Pharmacol.63(4):799-807.PMID: 12644580
- Deane FM. Synthesis and evaluation
of novel ellipticines as potential anti-cancer agents. Org Biomol
Chem. 2013 Feb 28;11(8):1334-44. doi: 10.1039/c2ob27186a
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